{"id":1336,"date":"2024-07-23T10:30:21","date_gmt":"2024-07-23T14:30:21","guid":{"rendered":"https:\/\/www.allergy-associates.com\/?p=1336"},"modified":"2024-07-23T10:30:21","modified_gmt":"2024-07-23T14:30:21","slug":"islet-cell-transplant","status":"publish","type":"post","link":"https:\/\/www.allergy-associates.com\/?p=1336","title":{"rendered":"Islet Cell Transplant&nbsp;"},"content":{"rendered":"\n<p>The FDA has recently approved the first pancreatic islet cell transplant for some type I diabetics.&nbsp; By way of clarification, type I diabetes is due to loss of the pancreatic islet cells and therefore a lack of insulin.&nbsp; Whereas; type II diabetes is due to insulin resistance because the islet cells are over producing insulin due to obesity.&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p>Most type I diabetics can be treated with insulin, either by injection or continuous infusion.&nbsp; But in a small minority safe control cannot be established with insulin.&nbsp; It is this group of fragile diabetics where the transplant has value.&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p>The islet cells are obtained from a single deceased donor pancreas and infused into the portal vein of the liver.&nbsp; Since they are from an unrelated donor, immunosuppressant drugs are required as in other organ transplants.&nbsp; So far, the procedure has had long term (&gt;5 years) success in only 1\/3 of recipients.&nbsp; But the concept is a novel one and improvements are likely to occur.&nbsp;&nbsp;&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The FDA has recently approved the first pancreatic islet cell transplant for some type I diabetics.&nbsp; By way of clarification, type I diabetes is due to loss of the pancreatic islet cells and therefore a lack of insulin.&nbsp; Whereas; type II diabetes is due to insulin resistance because the islet cells are over producing insulin due to obesity.&nbsp;&nbsp;&nbsp; Most type I diabetics can be treated with insulin, either by injection or continuous infusion.&nbsp; But in a small minority safe control&#8230;<\/p>\n<p class=\"read-more\"><a class=\"btn btn-default\" href=\"https:\/\/www.allergy-associates.com\/?p=1336\"> Read More<span class=\"screen-reader-text\">  Read More<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[174,655],"class_list":["post-1336","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-diabetes","tag-islet-cell"],"_links":{"self":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts\/1336","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1336"}],"version-history":[{"count":1,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts\/1336\/revisions"}],"predecessor-version":[{"id":1337,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts\/1336\/revisions\/1337"}],"wp:attachment":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}