{"id":1306,"date":"2023-12-07T11:39:45","date_gmt":"2023-12-07T16:39:45","guid":{"rendered":"https:\/\/www.allergy-associates.com\/?p=1306"},"modified":"2023-12-07T11:39:45","modified_gmt":"2023-12-07T16:39:45","slug":"chronic-ppi-use-and-asthma","status":"publish","type":"post","link":"https:\/\/www.allergy-associates.com\/?p=1306","title":{"rendered":"<strong>Chronic PPI Use and Asthma<\/strong>"},"content":{"rendered":"\n<p>New research shows that prolonged use of proton pump inhibitors (PPI\u2019s) can increase the risk for developing asthma.&nbsp; PPI\u2019s are the \u201cdrugs of choice\u201d for esophageal reflux, gastritis and gastric ulcers.&nbsp; But their long-term use impacts the gut microbiome which in turn can cause immune dysregulation.&nbsp; It is this \u201ctilting\u201d of immune function that increases the risk for asthma.&nbsp; Prolonged use of PPI\u2019s by women during pregnancy also increases the risk for their child to develop asthma.&nbsp;<\/p>\n\n\n\n<p>One strategy to lessen this risk is to use the PPI to gain control of the problem and then segue to an H2 antihistamine such as Pepcid (famotidine).&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New research shows that prolonged use of proton pump inhibitors (PPI\u2019s) can increase the risk for developing asthma.&nbsp; PPI\u2019s are the \u201cdrugs of choice\u201d for esophageal reflux, gastritis and gastric ulcers.&nbsp; But their long-term use impacts the gut microbiome which in turn can cause immune dysregulation.&nbsp; It is this \u201ctilting\u201d of immune function that increases the risk for asthma.&nbsp; Prolonged use of PPI\u2019s by women during pregnancy also increases the risk for their child to develop asthma.&nbsp; One strategy to&#8230;<\/p>\n<p class=\"read-more\"><a class=\"btn btn-default\" href=\"https:\/\/www.allergy-associates.com\/?p=1306\"> Read More<span class=\"screen-reader-text\">  Read More<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[638,639,406],"class_list":["post-1306","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-famotidine","tag-pepcid","tag-ppi"],"_links":{"self":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts\/1306","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1306"}],"version-history":[{"count":1,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts\/1306\/revisions"}],"predecessor-version":[{"id":1307,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=\/wp\/v2\/posts\/1306\/revisions\/1307"}],"wp:attachment":[{"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1306"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1306"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.allergy-associates.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1306"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}